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[Other Drugs] an investigation into clascoterone

  • 5months ago

  • 649
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I think the "concept" itself is quite attractive for clascoterone (Britzula) who is talking about this time. It is not a method of lowering DHT from the whole body like Pina/Duta, but a local mechanism that prevents androgen receptors (AR) in the scalp (skin), so in theory, there is an expectation that it can reduce concerns about systemic side effects. 

However, in terms of "how is the public opinion", expectations have grown again recently. The reason is that Cosmo announced six-month top-line results for Phase 3 (SCALP 1/2) of 5% solution for male AGA in December 2025, with significant TAHC (target hair count) improvements. 
According to the company and media, the 12-month safety follow-up will be completed in the spring of 2026 and regulatory submission (FDA/EMA) will be carried out. "Isn't it really on the commercialization rail?" 
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