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Generic drugs, which we often call 'copy drugs' and 'replicating drugs', are drugs made based on the pharmacological components of commercially available drugs. Once a new drug is discovered, the discoverer will be able to exercise the patent rights of the drug for 20 years and enjoy a monopoly in the market. When a drug's patent expires, other companies can manufacture and sell the same drug, and these latecomers are called copy drugs or generic drugs. Usually, it is cheaper than the original drug that enjoyed the patent right, and the existing original drug and formulation are changed.  From the patient's point of view, you may wonder whether it is okay to take these copy drugs, and whether the drug will be less effective or other side effects will occur compared to the original drug. In conclusion, you can take copy medicine. This is because copy drugs sold in Korea have passed the Ministry of Food and Drug Safety's biological equivalence and interchangeability evaluation. The biological equivalence experiment is an experiment in which the original drug and the copy drug are administered randomly to the experimenter and the blood concentration of the drug's main component or active metabolite is measured to demonstrate that the bioavailability is the same. In other words, if the drug concentration in the body is statistically equivalent, whether the original drug or the copy drug is administered, the copy drug has passed the biological equivalence test.  Since the biological equivalence test is a test to check whether ingredients that have already been proven effective are present in the body at a constant concentration for a certain period of time, the procedure is simpler than clinical trials aimed at developing new drugs, and the number of subjects required is relatively small, with 24 to 36. There are many small pharmaceutical companies in Korea, and even these pharmaceutical companies have relatively easier access to biological equivalence tests than new drug development, so many copy drugs are sold on the market.  However, in biological equivalence experiments, the criteria for determining statistical equivalence of drug concentration in the body are complex and sometimes misunderstood. Statistical equivalence of biological equivalence experiments is indicated in Article 17 of Chapter 2 of the Drug Equivalence Test Standards announced by the Ministry of Food and Drug Safety, and some misunderstand that copy drugs should not be taken because the underlined phrase in the photo is misunderstood as "test drugs are equal if they are between 80 and 125% of the efficacy of the Great Treaty".  It does not mean 80-125% of the drug's effectiveness, and the average difference between the comparative evaluation of the test drug and the grand treaty that passed the notice standard is theoretically about the deviation of the original drug by batch, so it can be seen as an equivalent drug in terms of drug effectiveness. Therefore, you can take the copy medicine. However, sometimes people buy dutasteride or finasteride directly from overseas due to its low price, which is very dangerous. This is because it is very likely that these overseas direct drugs have not gone through the aforementioned biological equivalence. Therefore, if you are considering taking copy drugs, it is desirable to decide whether the product is approved by the Korea Food and Drug Administration, and you can check the approval in the k-orange book of the drug safety country. * Drug Safety Country K-Orange Book (https://nedrug.mfds.go.kr/searchBioeq) Previously, copy drugs and original drugs had the same drug effect and side effects, but in some cases, drugs from specific pharmaceutical companies are needed. There are active ingredients that exhibit pharmacological action in the medicines we take, and inert ingredients that are necessary to make these active ingredients in the form of medicines. Inert ingredients include coating agents, stabilizers, fillers, flavoring agents, diluents, preservatives, pigments, etc., which usually have no effect on the body, but in rare cases patients may develop allergic reactions. It is difficult to find such a rare allergic reaction in a biological equivalence experiment with 24 to 36 subjects, so if you have an allergic reaction to a specific preservative or pigment, you should use a drug from another pharmaceutical company that does not contain these ingredients. Hair loss pills may require long-term use. Therefore, it is best to take the medicine that works best for you after sufficient consultation with an expert.

I'm Kim Ji-seok, CEO of the Mammoth Hairline Clinic Busan branch, who stops worrying about hair loss.  Seborrheic dermatitis is a chronic inflammatory disease that is quite common, with about 3-5% of the population experiencing it.It's called seborrheic scalp inflammation or seborrheic dermatitis, which is Scalp Seborrheic Dermatitis (SSD) in English.The word Seborrheic is hard to pronounce and feels unfamiliar It is a disease that is associated with sebum and sebaceous land.Unfortunately, the exact cause of seborrheic dermatitis has not yet been identified. Sebum secretion, bacterial infection, fungal infection, immune status and environmental factors combined It is known to work. Among the fungi, the Malese fungus (originally normally on the skin) is considered to be the main cause.Seborrheic dermatitis is characterized by erythema and human snow. Simply put, the scalp becomes red and a lot of dead skin cells such as dandruff occur. The main symptom is the itchiness of the scalp. What those who suffer from hair loss will be most curious about is whether seborrheic dermatitis can cause hair loss if it occurs on the scalp."Chronic presence of hemostatic dermatitis on the scalp can cause hair loss!"There are reports that seborrheic dermatitis can cause resting alopecia while causing inflammation of the scalp, and above all, it can progress faster to androgenic alopecia. Here is a summary of the seborrheic dermatitis known so far in the Revie Article below.  Let me summarize what is known about scalp seborrheic dermatitis so far.1. Seborrheic dermatitis can cause hair loss.2. Zinc deficiency can contribute to seborrheic dermatitis. 3. Consumption of antioxidant-rich vegetables and fruits can alleviate seborrheic dermatitis.4. Seborrheic dermatitis is more prevalent in men5. People with Parkinson's disease are vulnerable to seborrheic dermatitis6. It is often seen in immunocompromised people.7. It's popular in the 30s and 50s.8. UV rays suppress seborrheic dermatitis9. Wet and cold conditions cause seborrheic dermatitis.Seborrheic dermatitis is treated with ointments or shampoos with antifungal drugs, shampoos with Zinc, and steroids.These treatments can help with acute exacerbations, but they don't stop you from refuting the worsening and alleviation of seborrheic dermatitis. You can think of it as symptom relief treatment.If you want to make your scalp strong against seborrheic dermatitis1. After shampooing, dry your scalp well with cold air2. If you sweat a lot, take care of your scalp not to be humid3. 20-30 minutes a day to expose the scalp to the sun4. Eating Vegetables and Fruits That Boost Your Immunity5. If you have a scalp itch, don't put it off and see the doctor quickly to treat it early!We looked into seborrheic dermatitis, a chronic inflammatory skin disease. As it is a seborrheic dermatitis that is difficult to cure, I hope this column will help you prevent it in advance through your usual lifestyle.If the scalp itch persists, don't hesitate to get treatment through quick treatment and diagnosis.reference materialsScalp Seborrheic Dermatitis: What We Know So Far Subject Area:  DermatologyAnne Kelly Leroy; Rita Fernanda Cortez de Almeida Daniel Lago Obadia;Sidney Frattini;Daniel Fernandes Melo Skin Appendage Disord (2023) 9 (3): 160–164.