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the effectiveness of zinc and copper
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Various information about the impact on dht.
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[Zinc] It is most effective to take it in the form of a capsule of Zinc Picolinate, and about 60 mg per day is taken. These zinc ingredients are often applied to shampoo, so it would be good to check when purchasing shampoo.
More than 100 needs side effects. Usually, an adult's human body contains 1.4 to 2.5 grams of zinc, which is mainly stored in muscles (a total of 655), and is also highly concentrated in red and white blood cells. Other tissues with high zinc concentrations include bones and skin, kidneys, liver, pancreas, retina, and prostate. The recommended daily intake of zinc for adults is 15 milligrams. The daily intake for people is 25 to 30 milligrams. When zinc is supplemented for specific needs, the dose range for men is 30-60 milligrams, and for women, it is 30-45 milligrams.
5) Strengthening skin resistance, treating dermatitis 6) Increasing learning efficiency 7) Promoting growth and development, improving nervous loss of appetite 8) Increasing insulin secretion 9) Stress defense 10) Preventing arteriosclerosis 14) Improving colds, acne, sickle cell anemia, ulcers, rheumatoid arthritis, eczema, and psoriasis Severe zinc deficiencies are uncommon, but they appear as recurrent infections due to skin changes and diarrhea, hair loss, mental disorders, and immune dysfunction. Severe zinc deficiencies rarely occur in developed countries, but many American people are special? The elderly have the lowest zinc deficiency. According to the survey data, the average amount of zinc absorption is only 47-67% of the recommended amount of zinc nutrition.
Several other physical symptoms that correlate with low zinc levels include a decline in the ability to see at night or a decline in the ability to discern cloudy light, development failure, atrophy of the testicles, ulcers in the mouth, white cover on the tongue, and bad breath.
The white spots on the nails also reflect the zinc state, meaning the wound healing power is poor. This is because a secondary zinc deficiency in ancestral injury may be the cause of lesions in several patients. It takes some judgment to figure out the meaning of these lesions. In other words, it is necessary to judge whether the white spots match the degree of ancestral damage. The best way to measure zinc status is to measure the amount of zinc in white blood cells. Other common tests, such as hair or blood tests, are not reliable.
1) Effect of DHT inhibiting all mechanisms acting on hair follicles Zinc has been shown to have the effect of inhibiting all 5-alpha-reducing enzyme activity, male hormone activity, and DHT's mechanisms acting on hair follicles. It is most effective to take it in the form of a capsule of Zinc Picolinate, and about 60 mg per day is taken. These zinc ingredients are often applied to shampoo, so it would be good to check when purchasing shampoo.
2) Zinc deficiency causes dermatitis and alopecia.-A lack of zinc (Zn) in the apple juice human body causes symptoms such as eczema and hair loss around the nose, nail deformities, taste (味覺) disorders, male infertility, and immune failure. 100% apple juice has a high content of zinc and is also good for digestion and absorption. In case of shortage, it shows acne, dermatitis, dandruff and hair loss, weak nails and hair, and light colored hair.
3) 育毛, sex hormone secretion, development, etc.-Kimchi and soup stew are used all year round in Korea, and in China, there is a saying that "100 vegetables are not as good as cabbage (百菜 如 White 菜)." Cabbage is 96% water.
Vitamin C or calcium, potassium and iron are higher than expected. In addition, zinc, a mineral necessary for the secretion and development of breast hair (育毛) sex hormones, is almost equivalent to eggs and meat. In particular, vitamin C is a good food for preventing colds because it is enough to consume only one cabbage leaf per day.
The main source of zinc is animal food. Meat, including beef, fish and shellfish such as oysters, crabs, and shrimp, and liver are good sources of zinc. Therefore, it can be said that the protein source foods contain high zinc content. It also contains trace minerals such as zinc and urea selenium, which have indispensable actions in making healthy hair or bones. These ingredients are easy to lose when refining or processing food, so it is necessary to consume them carefully.
It is also contained in grains, nuts, and seeds, but these plant foods are not utilized because they are not absorbed by combining with tin (fiber compound) acid.
Vegetable foods such as grains have less zinc content, but legumes, grains, and nuts among vegetable foods are a relatively good source of zinc due to their high absolute intake. In particular, grains contain a lot in embryos and outer shells, but a significant amount is lost during the milling process.
Zinc content of each food product (148.7 / oats 3.2 / turnips 1.2 / pumpkin seeds 7.5 / parsley 0.9 / ginger root 6.8 / lima beans 3.1 / potato 0.9 / garlic 0.6 / peeled and dried peas 4.2 / carrot 0.5 / buckwheat 2.5 / whole wheat 3.2 / black beans 0.4 / green beans 1.6 8.
1) Excessive intake of zinc inhibits the absorption of other minerals, i.e., iron or copper. When zinc is consumed in excess of 100mg per day, especially when consumed in excess of 2g per day, side effects such as diarrhea, convulsions, vomiting, dizziness, and decreased immune function are followed, so be careful.
2) Given the report that excessive intake of zinc lowers HDL, HDL is a desirable substance that lowers the incidence of heart disease by removing cholesterol in blood vessels, so avoid excessive intake of zinc more than necessary. For healthy people, it is most desirable to consume zinc properly through daily meals.
3) The major toxic effect of zinc occurs when it continuously absorbs more than 150 milligrams per day. These effects include anemia due to copper deficiency, a decrease in HDL cholesterol levels, and a decrease in immune function. If a large amount (2 grams per kilogram of body weight) is administered to cause poisoning symptoms, vomiting usually occurs, so serious poisoning is extremely rare.
4) Eating zinc-containing foods also helps strengthen the immune system. If you take 100 to 120mg of zinc a day for the first two to three days when you have a cold, the duration and degree of symptoms are also halved.
5) Never take more than 120mg a day. If you consume more than this, the effect is halved. Zinc is included in syrups for colds, and you can contact a nearby pharmacy for an appropriate amount.
6) For those who take zinc, it is essential to take copper. This is because copper and zinc complement each other, returning the possibility of heart disease that can occur when zinc content is too high in the body to a normal state. The copper dose should not exceed 2-3 milligrams per day
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It is involved in more than 200 kinds of enzyme actions, such as carbohydrate and protein metabolism, and one of them is a component of SOD. In the body, the choroid, optic nerve, prostate, muscles, bones, liver, kidney, brain, kidney, spleen, and skin are mainly high concentrations, and zinc deficiency affects these organs. Zinc has many functions. First of all, it is called diabetic minerals as a component of insulin, and it is called sex minerals by forming sperms, and it is called taste minerals by restoring taste by the action of the taste center and peripheral, it is called learning minerals by improving concentration, and it is called growth minerals by promoting growth and development.
·The recommended daily dose is 12.5 mg, and the ODIs are 22.5 to 50 mg, which is high in fish, seaweed, mushrooms, pork, pumpkin seeds, sunflower seeds, beans, eggs, and oysters.
·It has the effect of discharging lead, and consuming more than 2g of zinc a day causes copper deficiency.
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[Copper] It has been reported that taking 4-7 grams of Copper Type 2 (see below) daily significantly reduces the incidence of degenerative diseases when taking 4-7 mg of Copper Supplement daily. The World Health Organization (WHO) recommended daily dose is less than 10 mg. When choosing a product, it is recommended to choose one that comes in the form of copper peptide, copper-amino acid celates, copper protein celates, and copper glycinate (*in the ingredient list). 5-Alpha Reduction is an enzyme that converts testosterone to DHT, which comes in two forms. Type 1 is the "cutaneous type," which is most distributed in the sebocyte of the skin, but is also distributed in keratinocyte in the epidermis and hair follicles, papillae and sweat glands in the dermis, as well as fibroblasts. Type 2 is distributed in the internal root of the seminal, prostate, and hair follicles. Propecia? (Finasteride) has a higher affinity for type 2 and is very suitable for prostate hypertrophy. It is also an oral form of medicine that affects the whole body. Copperion, on the other hand, is more effective in inhibiting type 1, which preferentially produces DHT in the skin and can be given topically to the skin. Copperion acts on type 2 as well as 5-alpha reductase type 1, which inhibits type 1 at 1.9 micromolar (reducing activity by 50%) and type 2 at 19.2 microm.
The application of Tricomin is to supply sufficient copper to hair follicles to suppress DHT production in the scalp, because the Metabolically active copper; copper free to block 5-alpha reduction present in the body is less than 1 microgram in about 1 mililiter's blood.
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1. Copper (Copper=cu=copper) Supplies of 4 to 7 mg per day 90% of the antioxidant power of the human body depends on this mineral called copper. The lack of coppers in the body causes most degenerative diseases, so taking a certain amount regularly improves health and improves cell regeneration and skin reconstruction. In the body, the coppers move in the form of first copper (copper 1 or Cu+1) and second copper (copper 2 or Cu+2). Most of the coppers in the body take the form of coppers 2 (two), of which coppers induce cell regeneration and skin reconstruction are coppers 2. Copper 2 is also called the "metabolically active Copper." This Copper 2 is blue in the water and has a greenish blue color when made with cream, lotion or solution. Copper 1 (circle) has no cell regeneration or skin reconstruction function and shows no color in the water.
Generally, the recommended daily dose is 1 to 3 mg, but recent findings have reported that daily doses of 4 to 7 mg of Copper Supplement significantly reduce the incidence of degenerative diseases. The World Health Organization (WHO) recommended daily dose is less than 10 mg. When choosing a product, it is recommended to choose the one in the form of copper peptide, copper-amino acid celates, copper protein celates, and copper glycinate (*in the ingredient list)
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Is Copper Better Than Than Propecia® for Blocking DHT Production? Subject: Is copper more effective in inhibiting dht production than Propecia?
Recent research indicators that DHT that harms hair follicles comes from the skin's sebocytes and sweet lands. (Chen et al 1996) A recent study has found that dht, which has an adverse effect on hair follicles, comes from sebocytes and sweat glands in the skin.
5 alpha-reductase, the enzyme system that converts the testosterone into DHT occurs into two enzyme forms. The enzyme system that transforms testosterone into dht, 5 alfariductase, occurs in two forms of enzyme.
The type 1 represents the 'cutaneous type'; it is located in the skin's sebocytes but also in epidermal and follicular keratinocytes, dermal papilla cells and sweet lands as well as fibroblasts. Type 1 is located in the sebaceous glands of the skin, and is as present in the epidermis, hair cells, dermal papillae, and sweat glands as well as fibroblasts.
Type 2 is mainly located in the seminal vesicles, prostates and the inner root sheath of the hair particles.
It must be administered by pills that spread the drug through the body. Propecia® (Finasteride), which has a higher affinity with type 2, is best suited for controlling prostate hypertrophy.
It should also be taken in the form of a pill that can spread the medicinal effects throughout the body.
Copper ion in the skin is more effective in inhibiting the type 1 form which is primally producing the DHT that damages followings and can be administered locally to the skin. The copper ion in the skin is more effective in suppressing type 1, which produces dht, which mainly damages pores, and can be administered locally on the skin.
Sugimoto et al (Sugimito 1995) found that copper ions are a potent 5α reductase inhibitor of 5-alpha reductase and both types of 5-alpha reductase (both type 1 and type 2) and the only metal to do so.
Copper ion inhibits (50% reduction in activity) type 1 alpha reductase at 1.9 micromolar (0.12 micrograms copper ion per milliliter)
and type 2 alpha reductase at 19.2 microM (1.2 micrograms copper ion per milliliter). No other metal has these effects. Copper ions inhibit both types, and other metal components do not have these effects.Omitted The application of copper-peptides may provide efficient copper into the hair particle area to block DHT production in the scalp. If you use copper peptide, you will be able to supply enough copper ions into your pores and suppress the dht production in the scalp area.
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The principle and countermeasures of hair loss The hormone that directly causes hair loss is known as dihydrotestosterone (DHT).
DHT is a metabolite produced by the action of a reducing enzyme called 5α-reductase on testosterone, a male hormone, which combines with a specific part of the hair follicle cell to cause a series of changes related to hair loss.
In addition, DHT shortens the growth period and lengthens the rest period during the hair growth cycle, so the hair falls out as the growth cycle continues.
Testosterone is affecting the growth of armpits and conspiracies, while DHT is affecting beard and hair.
However, it does not affect the growth of hair, but only the hair is affecting the fall (brain).
Step 1: Testosteron is converted to DHT by 5α-reductase enzyme Step 2: When DHT binds to the hair follicle's androgen receptors Step 3: Inhibition of protein synthesis due to protein synthesis inhibition and reduction of hair follicles, hair becomes thinner and grows shorter,
Step 4: Increased hair loss intensifies due to increased hair loss leaving hair follicles The DHT production inhibitory component 5α reductase is a reductase that converts testosterone, a male hormone, into dihydrotestosterone (DHT), a more potent hormone.
5α reductase is divided into type 1 and type 2. Type 1: Distribution of DHT in the epidermis and sebaceous glands (DHT amount produced = 30-40%) Type 2: Distribution in the outer wall of hair follicles and the prostate (DHT amount produced = 60-70%) To suppress DHT, it is important to suppress 5α reductase. Substances that suppress type 1 include cadmium, copper, and zinc, and substances that suppress type 2 are inhibited by copper.
Copper (Cu) is included in both type 1 and type 2 inhibitions.
Health supplements and foods that inhibit DHT production 1. Coprep peptide: inhibiting both type 1 and type 2 of 5α reductase 2. olive oil and oleanolic acid (extracted from olive leaves) 3. pyridoxine (vitamin B6) 4. gamma-linolenic acid (ground acid) 5. green tea
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Trichomine Trichomine is a product containing essential amino acids, minerals and follicle regeneration ingredients specially formulated with copper enzymes (Prezatide copper acetate and copper tripeptide-1), including hair follicle sprays and conditioning shampoos.
Function of coppers in hair follicles Both types 1.5 alpha reductase 1 and 2 are suppressed: Fundamentally preventing hair loss 2. Promoting extracularly matrix synthesis: normalization of hair growth and regression 3. Increasing fiber bundle density in hair papilla: Makes thin hair thick like normal hair.
4.Vascularization & Function Enhancement: Sufficient Nutrition for Hair follicles 5.Promoting natural growth factor synthesis: Accelerating hair growth 6.Strong anti-inflammatory action: Prevention of hair loss due to inflammation of the scalp
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1) Currently, the U.S. Food and Safety Administration (FDA) only recognizes two drugs: Propecia, a drug taken as a treatment for baldness, and Minoxidil, a drug applied. It has been reported that hair loss prevention and treatment effects are effective in about 20-30% of minoxidil and 60-70% of propecia.
① Propecia: Propecia was approved by the Food and Drug Administration (FDA) for the treatment of male hair loss in the second half of 1997. Propecia contains 1 mg of a substance called pinasteride, which inhibits type 2 5-alpha reductase (reductase). When this enzyme meets testosterone (male hormone), it turns into DHT, which causes hair loss. Thus, inhibition of this enzyme may inhibit it from becoming DHT hormone, a hair loss factor.
However, Propecia is only effective on the top of the head and not on complete baldnessAccording to the Nolwood classification, it is only effective in stages 2 to 5 of the entire 7-stage baldness process. If you stop taking it, it returns to its original state within two to three months, so there is a disadvantage that you have to take it for life to maintain its effectiveness. Two to three out of 100 people complain of erectile dysfunction and decreased libido due to side effects of Propecia. In particular, in the case of men in their 40s or older, their sexual function begins to decrease physiologically, and psychologically, it is easy to think that their sexual function has decreased due to professionalism. In patients over 50 years of age, Propecia is said to be ineffective.
② Minoxidil: was initially used as a treatment for hypertensive patients, but was found to have a head as a side effect, so it was used as a treatment for hair loss. It takes effect two to three months after use and sometimes loses more hair in the early stages, but it improves over time. Although it is a hair loss treatment that can be used by both men and women, minoxidil is also effective only on the top of the head where hair loss is progressing and not on the front of the scalp, which clearly shows baldness. In addition, it takes 6 to 12 months to confirm the effectiveness. If you don't apply it to the scalp twice a day, it won't work. Most Minoxidil users do not see a noticeable effect, and those who see it grow a little bit.
If Minoxidil is stopped from being used, hair loss will reappear, and new hair will be eliminated within two to three months.
Tretinoin (Steva A, Letin A) Tretinoin is a vitamin A derivative that promotes the growth and differentiation of hair follicle cells and breaks the connection between keratinocytes, leading to the elimination of old keratinocytes. When used in combination with minoxidil, it has a synergistic effect.
Trichomine Trichomine is a product containing essential amino acids, minerals and follicle regeneration ingredients specially formulated with copper enzymes (Prezatide copper acetate and copper tripeptide-1), including hair follicle sprays and conditioning shampoos.
Function of coppers in hair follicles Both types 1.5 alpha reductase 1 and 2 are suppressed: Fundamentally preventing hair loss 2. Promoting extracularly matrix synthesis: normalization of hair growth and regression 3. Increasing fiber bundle density in hair papilla: Makes thin hair thick like normal hair.
4.Vascularization & Function Enhancement: Sufficient Nutrition for Hair follicles 5.Promoting natural growth factor synthesis: Accelerating hair growth 6.Strong anti-inflammatory action: prevention of hair loss due to inflammation of scalp 2) Non-drug drugs Until now, it has been known as treatments for baldness in Korea rather than specialized drugs. Hair loss products or shampoo products, which are mainly applied, have become popular in the drug market. In addition, hair growth foods include Morinaga, which uses black beans, kelp, and yeast as raw materials. Most of the main ingredients of non-drug products are plant extracts.
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