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Effects of Hair Loss Drugs on Depression RISK by MetaAnalysis | Korea's No.1 Hair Loss Community, DAEDAMO

맘모스헤어라인의원 부산점 · 2024-01-25T16:30:46+09:00

Im Kim Jiseok director of the Mammoth Hairline Clinic Busan branchSome people complain that they feel depressed when they start taking Pinasteride Product Name Propecia or Dutasteride Product Name AvodatEven if you dont use the expression of depression some people say they feel weak or subduedDoctors should not ignore the patients symptoms This is because the symptoms the patient complains of are important signals from the bodyIf you talk about depression after taking hair loss pills it is very likely that you will hear the answer that it is not related to the drugIt is often explained that changes in emotions caused by hair loss drugs are unlikely because the interaction between hair loss drugs and depression is not clearly identifiedI think its time to change little by littleMeta Analysis is a research method that analyzes the results of papers written so far In particular when there are papers with conflicting results the meaning growsCurrently opinions are divided among doctors as papers on hair loss drugs and depression produce conflicting results In these cases metaanalysis has important implicationsWe analyzed six papers in the metaanalysis The total number of participants included in the six papers was 265672the conclusion of a metaanalysis15alphareducing enzyme inhibitors 5ARIs may significantly increase the risk of depression RR 18925alphareducing enzyme inhibitors 5ARIs mainly cause mild depression RR 211The good news is that hair loss drugs 5alphareducing enzyme inhibitors can cause mild depression rather than severe depressionThe alarming news is that the explanation that hair loss medication has nothing to do with depression seems to be the time to stopIf youve experienced depression often or if youve been diagnosed with depressionPatients who receive it should be careful when prescribing hair loss drugs for the first timeMechanisms and principles by which hair loss drugs 5alphareducing enzyme inhibitors can cause depressionThe 15alphareducing enzyme is also involved in the production of neuroactive steroids neuroactive steroids and can also act on the brain by passing through the cerebrovascular barrier BBBgt Therefore hair loss drugs can inhibit the production of various neuroactive steroids required by the brainA 25alphareducing enzyme inhibitor inhibits the production of allopregnanolone components preventing GABA receptor activity3Since GABA is a representative inhibitory neurotransmitter it is an essential substance to control emotions and find stability in stressful situations If the GABA concentration is low it can be vulnerable to symptoms such as anxiety depression and insomniaIn August 23 the FDA approved Zuranolone as a treatment for postpartum depression The ingredient of this drug is the principle of treating depression by acting on GABA receptors and activating GABA receptorsIf the GABA receptor is not activated properly you can think of it as a decrease in emotional stability and an increased risk of exposure to depressionSimply a male hormone inhibitor would it cause depression This simple approach must stop now If you look deeply into the mechanism and principle of action of the drug it is likely to cause depression enoughIf you take hair loss medicine and have any changes in your emotions please consult your doctor right away Above all if you are taking drugs for depression please let your doctor know before taking the hair loss medicine As of yet the American Urology Association and the European Urology Association AUA do not recognize depression as a side effect of the EAU 5alphareducing enzyme inhibitorI think there is a high possibility that this part will be revised in the future as steady papers and research progressAs a result of indepth discussions with the incumbent professor of psychiatry at the National University he said that for patients diagnosed with depression or who often suffer from depression the prescription of hair loss drugs in the 5alphareducing enzyme inhibitor series requires caution