The key action principle involved in the prevention of hair health and hair loss by biotin (water-soluble vitamin B7) is "structural strengthening of hair through the promotion of protein metabolism."The specific mechanisms of biotin on hair in the body can be divided into three.
1. About 80 to 90% of the synthesis and reinforced hair of keratin structures is made up of a protein called keratin. Biotin acts as a coenzyme to help bind the amino acids that make up this keratin (especially those that contain sulfur, such as cysteine and methionine).Principle: Biotin absorbed in the body promotes keratin protein production from the gene expression stage.The result: The tissue structure of the hair strands becomes denser, making the hair thicker and less easily broken or cracked.
2. Facilitating Metabolism through Carboxylase Activation Biotin acts as a binding partner for four essential carboxylases in the body, turning energy metabolism of hair follicle cells.Fatty acid synthesis (ACC enzyme activation): aids in the synthesis of essential fatty acids that make up the sebaceous glands and follicle cell membranes of the scalp. It prevents the scalp from becoming dry or inflamed, creating a soil that is good for hair to grow.Amino Acid and Glucose Metabolism: Hair root cells need huge amounts of energy to constantly divide and grow, accelerating the process of biotin converting nutrients into energy (ATP).
3. Hair Bulb cell's growth cycle optimization hair repeats the cycle called the growth-degenerate-rest period. When biotin is deficient, the hair follicle cell's energy is depleted, shortening the growth period, and the hair quickly enters the rest period (demolition period) in an immature state. Biotin helps to activate hair cells, supporting the hair to maintain a stable growth state.
** Medical Fact Check (Note) Excellent for Deficient Hair Loss: Biotin definitely helps with nutritional deficiency hair loss (rest hair loss) and hair weakness caused by disproportionate diet, stress, diet, reduced intestinal beneficial bacteria, etc.Limitations of Male Hair Loss (AGA): It does not block the "fundamental cause (hormone blocking) of male and female androgenic hair loss caused by heredity or DHT hormones. However, even in this case, it acts as an auxiliary role to make the existing hair thick and strong.
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