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Low-Level Laser Therapy (LLLT): A Study on the Recent Study
Hello, Apgujeong Mammoth Hairline I'm Nam Dowoo. ​ With the recent increase in interest in hair loss treatment, Low power,Low-level laser treatment or low-dose or red light treatment be called in various terms such as LLLT(Low Level Laser Therapy) A study on the efficacy and application of It's going on continuously. ​ especially AGA(androgenic alopecia) in therapy LLLTA number of studies have been published to prove the effectiveness of, In this great column, based on the results of recent research LLLTI'd like to examine the therapeutic effect of and its applicability. ​--------------------------------------------------------------------------------------------------- 1967year Endre Mesterlow power in shaven mice 694-nm Ruby Laser is the first to report promoting hair regeneration.<Dr. Endre Mester>This discovery is LLLTwas an important turning point, suggesting that may be effective in treating hair loss. But LLLTgo AGA It's been scientifically verified for its impact on treatment the first randomized controlled trial(RCT)a long time after 2009progressed in the year Hair Max Laser Comb It's made up of research.<Hairmax Laser comb>until now LLLT studies have shown thatLLLTIt has shown that it has the effect of increasing the number of hair and the thickness of the hair,Existing studies had some limitations.First of all, participated in the study the number of patients was smallwith an air of, LLLT The treatment period was relatively shortHere we go. also, I didn't consider my scalp condition, There were many cases where the subjects of the study did not represent the actual group of hair loss patients well.​The research we're going to find out today is being evaluated as a practical study that has overcome these limitations .China SunInf Technology(Slinph Technology Co., Ltd)produced by iHelmet(the United States FDA Approval, K162782) Using a low-level laser treatment device, In this study, the past 5We used thousands of user data every year to analyze treatment outcomes. The study is mild AGA to the patient 38Week, Moderate-Severe AGA to the patient 40We've had a week of treatment.<iHelmet>Low power laser treatment(LLLT) To evaluate the effectiveness of the helmet from various angles Total 6I set and analyzed the items. ​ Does the scalp oil secretion decrease: The participants in the study were LLLT After the treatment, we evaluated whether the oil secretion in the scalp decreased. A decrease in oil secretion can mean an improvement in scalp condition, This can contribute to suppressing hair loss progression. Does scalp dandruff decrease: We evaluated the dandruff reduction. Dandruff is an important indicator of the health of the scalp, If the dandruff decreases, it can be seen that the scalp condition has improved. Does the scalp rash decrease: We evaluated if the scalp rash decreased after the treatment. The reduction of the rash is LLLTmay suggest that may alleviate the scalp inflammatory response. Decreased daily hair loss: Evaluate your daily hair loss to see if it's reduced, LLLTdetermined if was actually effective in reducing hair loss. New hair growth or increased hair density: We evaluated whether new hair grew or existing hair density increased after treatment. Increased hair density is an important indicator that hair loss is improving. Hair thickness change: I evaluated whether my hair became thicker. The increase in hair thickness is LLLTcan have a positive effect on. ​These 6We gave scores through evaluation of various items,After that, we evaluated the overall efficacy by summing up the total scores. (No effect/an intermediate effect/a considerable effect)​Efficacy Evaluation Results: mild AGA Patient: LLLT Helmet treatment 51.9%a mild case of AGA to the patient "an intermediate effect"with a view to, 27.7%To "a considerable effect"represented by. mild overall AGA a patient's medicine 79.6%He responded positively to the treatment. ​ Moderate-Severe AGA Patient: Moderate-Severe AGA among the patients 57.4%experienced a moderate effect, 20.0%showed a significant effect. due to this, the degree of moderation-Severe AGA a patient's medicine 77.4%has had a positive treatment effect. ​This study is LLLT Helmets are mild and moderate-Severe AGA It shows that it can be an effective treatment option for both patients. Overall LLLT The clinical effect of helmet therapy is medicine 80%at the end of, This is a fairly positive result for the patients in the study. Also, this study is LLLTWe presented insights into the characteristics and optimal duration of treatment of androgen hair loss patients who would recommend.​First, a male useraccording to the results of the study, Male patients are more likely than female patientsLLLT There was a tendency to get a better efficacy evaluation in treatment. This means that men's hormonal conditions and the degree of hair loss progression LLLTsuggest that it may affect the response of. Men may generally have faster hair loss progression due to hormonal changes, LLLTcan be effective for these hormone-dependent hair loss.​second child, 180More than one time of treatment or 1use for more than years LLLT It has been shown that the effectiveness of treatment can increase with the number and duration of treatment. 180Patients who have been treated more than once, and the duration of the treatment 1For patients who have been older than that I got a better efficacy evaluation. This is LLLTindicating that long-term use of helps promote hair growth and suppress hair loss. The longer the treatment period, the more pronounced the effect on hair regeneration can be.​Third, scalp dandruff, rash, If you have itching dandruff, rash, Patients with inflammatory symptoms or irritation of the scalp, such as itching LLLT He responded more positively to the treatment. This is LLLTsuggests that can help improve blood flow in the scalp and relieve inflammation. If your scalp is not in good condition, LLLTIt can improve scalp health and promote hair growth.​These characteristics and insights into the duration of the treatment are in actual clinical practice LLLTto make effective use of It provides important information. I'm going to make a patient-specific treatment plan, By controlling the duration and frequency of treatment LLLTcan maximize the effectiveness of.​This study has one difference from previous research results,In previous studies LLLT Treatment includes finasteride or minoxidil, etc When combined with medication or external applicationIt has been reported to have synergistic effects that further increase hair diameter and density,In this study LLLTand minoxidil at the same time, LLLTWhen I did the same thing with the finasteride,No greater synergy was found than the effect of monotherapy. ​A conclusion is, This study is for the treatment of androgenic hair loss LLLTIt's a study that demonstrates the actual effectiveness of in many patient groups,iHelmetusing The overall clinical effect is medicine 80%​at the end of, The recommended treatment is 1for more than years or 180more than one timeIt's the use of. a male patientWow, on my scalp ​dandruff, rash, itchingin patients withIt's expected to be more effective. The results of this study are Next LLLTTo ensure effective use of and access to patient-specific care It is expected to be an important reference.---------------------------------------------------------------------------------------------------- In addition to As I mentioned earlier in the article,LLLT There are many other studies related to this, Let me summarize it briefly. ​Various wavelengths and instruments in various studies, The experimental design was used, Most studies include double-blindness, including control groups, in a randomized controlled trial I presented reliable results.only, The limitations of the study are that there are few subjects and the short duration of the study.---------------------------------------------Avram et al. (2007) male alopecia(AGA) Patient 7for the sake of the Ming LLLTIt's an early study that applied that. 655nm wavelength Suntec Use a laser Week 2Raw fish 20for each minute 3~6I treated him for months. As a result, an increase in fluff and seed hair was observed, It was not statistically significant due to the small number of samples. There was no improvement in the overall evaluation.Summary: LLLTSome improvements were observed, but small studies made it difficult to draw meaningful conclusions.​Leavit et al. (2009)This study is HairMax Lasercomb®of FDA for approval 110name AGA for patients double-blindness, We conducted a placebo-controlled experiment. LLLT The group is 19.8 hairs/cm²showed increased hair density of, The placebo group is 7.6 hairs/cm² It's decreased. The side effects are minor, There was also a statistically significant difference.Summary: Large sample size and double-blind design LLLThad a positive effect on hair growth.​Kim et al. (2014) 40name AGA for patients double-blindness, We did a placebo-controlled experiment, 630nm, 660nm, 650nm wavelength-emitting LED I used a helmet. LLLT The density of hair in the group 17.2 hairs/cm² It's increased, Satisfaction and overall assessments showed no significant difference from the control group.Summary: Hair density increased, There was no statistically significant difference in satisfaction or subjective evaluation.​Lanzafame et al. (2013) 18~48three men AGA Patient 41for the sake of the Ming
Mammoth Hair Restoration Center, Apgujeong
Why curls occur after hair transplantation
~Hello, Plastic surgery even on windy daysI'm Park Suho. ​There are people who say that transplant hair grows into curly hair after hair transplantation. Why is that?I don't know the exact cause yet.  Nelson BR, Griffiths CEM, Stough DB, et al. Curly lusterless hair: anatomic surface changes on transplanted hair shafts. J Derm Surg Oncol. 1993;19:1129-1130.​There are many hypotheses, and among them, I will let you know what I researched and presented.At the World Hair Transplant Society conference in Lisbon, Portugal, I also received a small award on this topic. ~Patients who said "transplanted hair cannot be dyed" after hair transplantation often had curly hair. If it doesn't dye, I thought there would be a change in the cuticle layer and looked for the eye door. (The cuticle layer is a layer that is scaly on the outermost side of the hair.) There are papers on cuticle changes after hair transplantation. Sadick NS, Hashimoto K, Teichberg S. Acquired posttransplantation hair kinking. Dermatol Surg. 1995;261-262. Nelson BR, Griffiths CEM, Stough DB, et al. Curly lusterless hair: anatomic surface changes on transplanted hair shafts. J Derm Surg Oncol. 1993;19:1129-1130.After the hair transplant, I observed the curly hair with an electron microscope, The cuticles of graft hair grown with curly hair were irregular in thickness and shape. However, he ended up saying that the cause was unknown and that further research was needed. So I decided to observe the hair follicles under a microscope, not the hair. ~There are people who want to get rid of the area altogether because the density is too low after hair transplantation. In that case, we will reduce the height of the forehead by removing the skin from the previously transplanted area through forehead reduction.That kind of person came, Among the hair that is loose in the transplanted area, we selected hair with severe curls and observed the scalp tissue under a microscope.  Director Song's father, who worked with him at Mojerim Plastic Surgery, has been doing skin pathology for a long time We were able to study pathologies that we didn't know well, I was able to present the results as a presentation and thesis.  I learned a lot about basic hair pathology while listening to the professor's explanation.Once again, I would like to express my gratitude to Director Song and Professor Song by borrowing this article!The picture below is an abstract of a paper published in the forum of the World Hair Transplant Society.  ~Let's take a look at the first hair that has a lot of curls.You see white scarring underneath the hair follicle (yellow circle), and under the microscope you see the hair follicle pressed against the red scar tissue. (Yellow arrow)If you zoom in on the follicles, I can see the hair follicles crushed in the scar tissue. The white asterisk is the cuticle layer, which at the lower level of the follicle is bound to the fundus house of the follicle.When you go to the higher level, the hair follicles and hair separate to become what we call hair cuticles. Originally, hair follicles are surrounded only by adipose tissue as shown in the picture below,The shape and thickness of each layer are uniform. normal hair folliclesHowever, if the scar tissue presses the hair follicle and deforms its shape, the shape and thickness of the cuticle layer are also deformed. Shall we look at one more picture? Fluffy (blue arrow), curly hair (green arrow), and curly hair (yellow arrow) that are just starting to grow. The hair follicles of curly hair are curved, and the hair follicles without curly hair maintain their shape well in a circle. If you zoom in a little bit,  The difference in shape is obvious.Shall we look at one last one? It's very curly hair.You can also see white scars around the hair follicles with the naked eye. The microscope shows that the hair follicles are severely deformed.It's been years since I had my hair transplant, and I still see inflammatory cells. (Yellow circle)Among the transplanted hair, there was hair that was not curly, so I observed it.  How is it? It maintains the shape of normal hair seen from above without any change in shape, right?There is a red scar tissue underneath the hair follicle, but fortunately, it is a little away from the hair follicle, so it did not transform the hair follicle.  Like this. ^^~So I came to a conclusion like this. One of the reasons for curly hair after hair transplantation is the deformation of the cuticle layer. Deformation of the cuticle layer is caused by deformation of the hair follicle. Deformation of follicles occurs because of scar tissue around follicles.Other hypotheses areIt is probably because the hair follicles are bent in a 'J' shape during the transplantation process.The transplanted follicles will bend under resistance in the process of breaking through the scarred skin. There's a back. It's all possible, but, At least in this study I learned that the deformed cuticle layer caused by scar tissue around the hair follicle can cause curly hair after hair transplantationCurly hair that occurs after hair transplantation usually spreads out after two to three years,It's similar to the period when scar tissue softens again.  ~To reduce the incidence of curly hair after hair transplantation, It may vary from patient to patient, I think I need experience and skills to minimize scarring. I guess that's why fewer people are uncomfortable with curly hair as time goes by compared to when you first start hair transplantation^^~ Plastic surgery even on windy daysIt was Park Suho
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